dichloromethane
密度:1.325
熔点:-97℃
沸点:-142.1° F (NTP, 1992)
折射率:1.4242
蒸汽压:448.0±0.0 mmHg at 25°C
形态:Liquid
PSA:0.00000
logP:1.42150
溶解度:Miscible in ethyl acetate, alcohol, hexanes, methanol, diethyl ether, n-octanol, acetone benzene, carbon tetrachloride, diethyl ether and chloroform.
Λ:λ: 235 nm Amax: 1.00λ: 240 nm Amax: 0.20λ: 250 nm Amax: 0.05λ: 260 nm Amax: 0.02λ: 340-400 nm Amax: 0.01
黏性:Viscosity is a measure of a fluid's resistance to flow. It describes the internal friction of a moving fluid.
蒸汽密度:2.9 (vs air)
分析实验室方法:Method: NIOSH 1005, Issue 3; Procedure: gas chromatography with flame ionization detector; Analyte: dichloromethane;; Matrix: air; Detection Limit: 0.4 ug/sample.
外观:无色透明液体,有芳香气味。
大气OH速率常数:1.42e-13 cm3/molecule*sec
自燃:1184° F (USCG, 1999)
存储:储存注意事项 储存于阴凉、通风的库房。远离火种、热源。库温不超过32℃,相对湿度不超过80%。保持容器密封。应与碱金属、食用化学品分开存放,切忌混储。配备相应品种和数量的消防器材。储区应备有泄漏应急处理设备和合适的收容材料。
自燃温度:556 °C
致癌性:Dichloromethane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
化学性质:Methylene chloride, a chlorinated solvent, is a volatile, colorless liquid with a sweet-smelling odor. It is often referred to as dichloromethane. Methylene chloride has many industrial uses, such as paint stripping, metal cleaning and degreasing.
物理属性:Clear, colorless liquid with a sweet, penetrating, ethereal odor. Leonardos et al. (1969) determinedan odor threshold concentration of 214.0 ppmv. The average least detectable odor thresholdconcentrations of technical grade methylene chloride in water at 60 °C and in air at 40 °C were 5.6and 24 mg/L, respectively (Alexander et al., 1982).
颜色:无色透明液体,有芳香气味。[1]
腐蚀性:Liquid methylene chloride; will attack some forms of plastics, rubber and coatings.
分解:It can be decomposed by contact with hot surfaces and open flame, and then yield toxic fumes that are irritating and give warning of their presence. When heated to decomposition it emits highly toxic fumes of phosgene; and /hydrogen chloride;/.
可燃性:Noncombustible. Dichloromethane vapor concentrated in a confined or poorly ventilated area can be ignited with a high-energy spark, flame, or high-intensity heat source.
汽化热:28.82 kJ/mol at 25 deg C; 28.06 kJ/mol at boiling point
亨利法律常量:2.49 at 30 °C (headspace-GC, Sanz et al., 1997)
电离电位:11.32 eV
气味:penetrating ether-like odour
气味阈值:The odour threshold of dichloromethane is about 200 ppm [694 mg/m3] (Stahl,1973).
物理属性:二氯甲烷(75-09-2 )的性状: 1.其外观呈无色透明易挥发液体。 2.具有类似醚的刺激性气味。 3.溶于约50倍的水,溶于酚、醛、酮、冰醋酸、磷酸三乙酯、乙酰乙酸乙酯、环己胺。 4.与其他氯代烃溶剂乙醇、乙醚和N,N-二甲基甲酰胺混溶。 无色透明易挥发液体。具有类似醚的刺激性气味。 溶于约50倍的水,溶于酚、醛、酮、冰醋酸、磷酸三乙酯、乙酰乙酸乙酯、环己胺。与其他氯代烃溶剂乙醇、乙醚和N,N-二甲基甲酰胺混溶。 外观与性状: 无色透明液体,有芳香气味。 熔点(℃): -96.7 沸点(℃): 39.8 相对密度(水=1): 1.33 相对蒸气密度(空气=1): 2.93 饱和蒸气压(kPa): 30.55(10℃) 燃烧热(kJ/mol): 604.9 临界温度(℃): 237 临界压力(MPa): 6.08 辛醇/水分配系数的对数值: 1.25 引燃温度(℃): 615 爆炸上限%(V/V): 19 爆炸下限%(V/V): 12 溶解性: 微溶于水,溶于乙醇、乙醚。
溶解性:微溶于水,溶于乙醇、乙醚。[15] 光谱特性:Index of refraction: 1.4244 @ 20 deg C/D
IR: 4354 (Coblentz Society Spectral Collection)
NMR: 6401 (Sadtler Research Laboratories Spectral Collection)
MASS: 117 (Atlas of Mass Spectral Data, John Wiley & Sons, New York)
IR PRISM: 6620 (gas), 1011, IR GRATING: 28523
Intense mass spectral peaks: 49 m/z, 84 m/z
稳定性:In the absence of moisture at ordinary temp, dichloromethane; is relatively stable when compared with its congeners, chloroform; and carbon tetrachloride;.
存储温度:Store at RT.
表面拉伸:28.20 dyne/cm at 25 deg C
毒性摘要:IDENTIFICATION AND USE: Dichloromethane; is a clear colorless, volatile, sweet-smelling lipophilic liquid. It is commonly used as a solvent in wood varnishes, paints, strippers, cements, vapor degreasing of metal parts. Methylene chloride; is also widely used as a process solvent in the manufacture of a variety of products including food, textiles, insecticides, herbicides, steroids, antibiotics and vitamins. Not registered for current pesticide use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. HUMAN EXPOSURE AND TOXICITY: Methylene chloride; is rapidly absorbed following inhalation, through the alveoli of the lungs into the systemic circulation. It is also absorbed from the gastrointestinal tract, and dermal exposure results in absorption but at a slower rate than via the other routes of exposure. Methylene chloride; is quite rapidly excreted, mostly via the lungs in the exhaled air. It can cross the blood-brain barrier and be transferred across the placenta, and small amounts can be excreted in urine or in milk. Its biotransformation by the hepatic mixed function oxidases (MFO) leads to formation of carbon monoxide; (CO) and elevated blood carboxyhemoglobin (COHb). Human exposure is mainly due to inhalation but there are incidences of toxicity from oral and dermal contact.Dermally, dichloromethane; irritates the skin and eyes especially when evaporation is prevented; prolonged contact may cause chemical burns. Following inhalation of dichloromethane; pulmonary edema, hearing loss, CNS depression, liver dysfunction, renal dysfunctions, cardiac stress, and effects on hematological parameters have been reported. Exposure at extremely high levels from use as a paint stripper by consumers or in an occupational setting, has been fatal. Dichloromethane; is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. ANIMAL STUDIES: Dichloromethane; is not teratogenic in rats or mice at concentrations up to 16,250 mg/cu m. Developmentally, dichloromethane; is able to cross the placental barrier, and minor skeletal variations, fetal weight reduction, and more rapid behavioral habituation was evident in rats exposed before and during gestation. Single ip injection of dichloromethane; (1330 mg/kg) into adult male rats caused renal proximal tubular degeneration. Morphological effects were observed in the cortex and the outer medulla. Prolonged exposure to high concentrations of methylene chloride; (> or = 17,700 mg/cu m) caused reversible CNS effects, slight eye irritation and mortality in several laboratory species. Neurological damage was reversible in rats exposed to 7, 100 mg/cu m dichloromethane; for 13 weeks via inhalation. Body weight reduction was observed in rats at 3500 mg/cu m and in mice from 17,700 m/cu m. Effects on the liver were noted in dogs continuously exposed to 3,500 mg/cu m for up to 100 days. After intermittent exposure, effects on the liver were observed in rats at 3500 mg/cu m and in mice at 14,100 mg/cu m. Other target organs are the lungs and the kidneys. Dichloromethane; is considered a carcinogen. When administered at levels of 0, 60, 125, 185 and 250 mg/kg body weight/day to mice in deionized drinking water; for 104 wk, the high dose male and female mice showed a transitory increase in mean leucocyte counts. There was a slight elevation of proliferative hepatocellular lesions in the treated males but no dose related trend was apparent and the effect was absent in the females. Neoplastic lesions observed in the study were homogeneous among all groups and were within the range of incidence in historical controls. The results of this study demonstrated a toxicological no observable effect level of 185 mg/kg body weight/day in both sexes. In a 2 year study, female rats exposed to 500, 1500, or 3500 ppm had an increase in the total number of benign mammary tumors in an exposure-related manner. This effect was also evident in male rats in the 1500- and 3500-ppm exposure groups. Male rats exposed to 1500 or 3500 ppm had an increased number of sarcomas located in or around the salivary glands. In contrast, hamsters exposed to the same concentrations had less extensive spontaneous geriatric changes, decreased mortality (females), and lacked evidence of definite target organ toxicity. Dichloromethane; is mutagenic in prokaryotic microorganisms with or without metabolic activation (Salmonella or Escherichia coil). In eukaryotic systems it gives either negative or, in one case, weakly positive results.